Hi, I started taking 'PuffPlus' four weeks ago one capsul with each main meal i.e. twice a day. At the time of deciding to try PuffPlus I was literaly gasping for breath by the time I'd climbed a flight of stairs. Now I have no trouble and my general well being is a lot better now that I breath clearly. Well worth the effort of giving it a try, my Daughter who has a simular problem with breathing on occasions is going to give it a try.